CURRICULUM VITAE
ÅSE MARIE HANSEN
Cand.pharm., Ph.d.
Previous professional experience
1986-93 Researcher, the National Research Centre for the Working Environment
1983-86 Analytical chemist, The DAK Laboratories
1982-83 Analytical chemist, National Food agency
Education
2003 Positive evaluation for professor position in chemical toxicology
1992 PhD, in the Royal Danish School of Pharmacy, Copenhagen
1982 MSc in Pharmacy in the Royal Danish School of Pharmacy
Publications
Published more than 95 peer-reviewed papers
Scientific production from 2006
Hansen, ÅM, Raaschou-Nielsen, O, Knudsen, LE. Urinary 1-hydroxypyrene in children living in city and rural residences in Denmark (2006) Sci Tot Environ. 363; 70-77.
Hansen, ÅM, Høgh, A, Persson, R., Karlson, B, Garde, AH, Ørbæk, P. (2006) Bullying at work, health outcomes, and physiological stress response. Psychosom. Research. 60; 63-72.
Carlsson, F, Persson, R, Karlson, B, Österberg, K, Hansen, ÅM, Garde, AH, Ørbæk, P. (2006) Salivary cortisol and self-reported stress among persons with environmental annoyance. Scand J Work Environ Health. 32(2); 109-120.
Hansen, ÅM, Persson, R., Garde, AH, Karlson, B, Ørbæk, P. (2006) Diurnal profiles of salivary cortisol on workdays among construction workers versus white-collar workers. Scand J Work Environ Health, suppl 2; 22-26.
Eek, FC, Garde, AH, Hansen, ÅM, Persson, R, Ørbæk, P, Karlson, B. The cortisol awakening response - an exploration of intraindividual stability and negative responses. Scand J Work Environ Health 2006;32(Suppl 2):15-21.
Karlson, B, Carlsson, F, Hansen, ÅM, Garde, AH, Österberg, K, Ørbæk, P. (2006) Diurnal cortisol pattern on a workday and day off in shift workers. Scand J Work Environ Health, suppl 2; 27-34.
Hansen, ÅM, Garde, AH, Hansen, J. (2006) Diurnal urinary 6-sulfatoxymelatonin levels among healthy Danish nurses during work and leisure time. Internat Chronobiol. 23(6); 1203-1215.
Eller, NH, Netterstrøm, B, Hansen, ÅM. (2006) Psychosocial factors at home and at work and levels of salivary cortisol. Biol Psychol. 73(3); 280-287.
Garde, AH, Faber, A, Persson, R, Hansen, ÅM, Hjortskov, N, Ørbæk, P, Schibye, B. (2007) Concentrations of cortisol, testosterone and glycosylated haemoglobin (HbA1C) among construction workers with 12-h workdays and extended workweeks. Int Arch Occup Environ Health. 80; 404-411.
Hansen, ÅM, Garde, AH, Eller, NH. (2007) Estimation of individual reference intervals in small sample sizes. Int J Hyg Environ Health. 210; 471-478.
Hougaard, KS, Hansen, ÅM. (2007) Enhancement of developmental toxicity by gestational stress. A review. Neurotoxicology and teratology. 29; 425-445.
Knudsen, LE, Hansen, ÅM. (2007) Biomarkers of intermediate endpoints in environmental and occupational health. Int J Hyg Environ Health. 210(3-4); 461-470.
Hansen, ÅM, Mathiesen, L, Pedersen, M, Knudsen, LE. (2007) Biomarkers of environmental and occupational PAH exposure. Focus on 1-hydroxypyrene in urine in Environmental impact of polycyclic aromatic hydrocarbons, Editor Chimezie Anyakora, ISBN-nummer 978-81-308-0188-9. K. Chapt. 5 pp 99-134. Research Signpost (www.ressign.com), India.
Hansen, ÅM. (2008) Respond to letter to the editor. Int J Hyg Environ Health. 211; 467.
Hansen, ÅM, Mathiesen, L, Pedersen, M, Knudsen, LE. (2008) Urinary 1-hydroxypyrene (1-HP) in environmental and occupational studies - a review. Int J Hyg Environ Health. 211; 471-503.
Hansen, ÅM, Garde, AH, Persson, R. (2008) Sources of biological and methodological variation in salivary cortisol and their impact on measurement among healthy adults – a review. SJCLI . 68 (6); 448-458.
Persson, R, Garde, AH, Hansen, ÅM, Österberg, K, Ørbæk, P, Karlson, B. (2008) Seasonal variation in salivary cortisol concentrations. Chronobiology. 25(6); 923-937.
Hansen, ÅM, Meyer, HW, Gyntelberg, F. Building-related symptoms and stress indicators. (2008) Indoor Air. 18(6); 440-446.
Lindeberg, SI, Eek, F, Lindbladh, E, Östergren, P-O, Marie Hansen, ÅM, Karlson, B. (2008) Exhaustion measured by the SF-36 vitality scale is associated with a flattened diurnal cortisol profile. Psychoneuroendocrinology. 33; 471-477.
Hansen, ÅM, Garde, AH, Persson, R. (2008) Measurement of salivary cortisol - effects of replacing polyester with cotton and switching antibody. SJCLI 68 (8); 826-829.
Österberg, K, Karlson, B, Hansen, ÅM. (2009) Cognitive performance in patients with burnout in relation to diurnal kortisol. Stress 12 (1), 70-81.
Persson, R, Hansen, ÅM, Ohlsson, K, Balogh, I, Nordander, C, Ørbæk, P. (2009) Physiological and psychological reactions to work in men and women with identical job tasks. European Journal of Applied Physiology 105; 595-606.
Garde, AH, Persson, R, Hansen, ÅM, Ősterberg, K, Ørbæk, P, Eek, F, Karlson, B. (2009) Effects of lifestyle factors on concentrations of salivary cortisol in healthy individuals. SJCLI 69 (2); 242-250.
Rod, NH, Hansen, ÅM, Nielsen, J, Schnohr, P, Grønbæk, M. (2009) Low risk factor profile and breast cancer risk among postmenopausal women – and a suggested hormonal pathway. Intern J Cancer. 124; 1935-1940.
Hansen, ÅM, Larsen, AD, Rugulies, R, Garde, AH, Knudsen, LE. (2009) A review of the effect of the psychosocial working environment on physiological changes in blood and urine. BCPT. 106; 73-83.
Ballegaard, S, Karpatschof, B, Nyboe, J, Trojaborg, W, Hansen, ÅM, Magnusson, G, Petersen, PB. (2009) Stress increases sensitivity of chest bone acupuncture point. SJCLI. 69 (6); 713-721.
Garde, AH, Hansen, ÅM, Hansen, J. (2009) Sleep length and quality, sleepiness and urinary melatonin among healthy Danish nurses with shift work during work and leisure time. IAOEH. 82; 1219-1228.
Persson, R, Hogh, A, Hansen, ÅM, Nordander, C, Ohlsson, K, Balogh, I, Österberg, K, Ørbæk, P. (2009) Personality traits among bullied employees and witnesses to bullying in the manufacturing industry. Motivation and Emotion. 33; 387-399.
Kristiansen, J, Mathiessen, L, Nielsen, PK, Hansen, ÅM, Shibuya, H, Petersen, HM, Lund, SP, Skotte, J, Søgaard, K. (2009) Stress reactions to open-plan office noise and cognitively mentally demanding tasks. Int Arch Occup Environ Health. 82 (5); 631-641
Hansen, ÅM, Blangsted, AK, Hensen, EA, Søgaard, K. Sjøgaard,GS. (2010) Physical activity, job demand-control, perceived stress-energy, and salivary cortisol I white-collar workers. IAOEH. 83; 143-153.
Rod, NH, Kristensen, TS, Diderichsen, F, Prescott, E, Jensen, G., Hansen, ÅM. (2010) Cortisol, estrogens and risk of ischemic heart disease, hormone-dependent cancers and all-cause mortality in postmenopausal women: a prospective cohort study. Int J Epidemiol. 39(2):530-8.
Persson, R, Österberg, K, Garde, AH, Hansen, ÅM, Ørbæk, P, Karlson, B. (2010) Seasonal variation in self-reported arousal and subjective health complaints. Psychology, Health & Medicine. 15(4); 434-444.
Harris, A, Waage, S, Ursin, H, Hansen, ÅM, Bjorvatn, B, Eriksen, HR. (2010) Shift work, Cortisol and Health among Offshore Workers. Psychoendocrinology. 35;1339-1347.
Jönsson, P, Wallergård, M, Österberg, K, Hansen, ÅM, Johansson, G, Karlson, B. (2010) Cardiovascular and cortisol reactivity and habituation to a virtual reality version of the Trier Social Stress Test: a pilot study. Psychoendocrinology. 35; 1397-1403.
Hogh, A, Mikkelsen, EG, Hansen, ÅM. (2010) Individual consequences of bullying/ mobbing at work. In Bullying and Harassment at the workplace. Taylor & Francis, London. ISBN: 978-1-4398-0489-6.
Hansen, ÅM, Høgh A, Persson, R. (2011) Frequency of bullying at work, physiological response and mental health. J Psychosom Research. 70(1); 19-27.
Eller, NH, Kristiansen, J, Hansen, ÅM. (2011) Long-term effects of psychosocial factors, at home and at work, on biomarkers of stress. Int J Psychophysiology. 79; 195-202.
Kolstad, HA, Hansen, ÅM, Kærgaard, A, Thomsen, JF, Kærlev, L, Kristensen, AS, Mors, O, Mikkelsen, S, Grynderup, MB, Ruguiles, R, Andersen, JH, Bonde, JP. (2011) Jobstrain and risk for depression: Is reporting biased? AJE. 173; 94-102.
Buttenschøn, HN, Kristensen, AS, Buch, HN, Andersen, JH, Bonde, JP, Grynderup, MB, Hansen, ÅM, Kolstad, HA, Kærgaard, A, Kærlev, L, Mikkelsen, S, Thomsen, JF, , Kofoed, P, Erhardt, A, Woldbye, DPD, Børglum, MD, Mors, O, (2011) The norepinephrine transporter gene is a candidate gene for panic disorder. J Neural Transmiss. 118(6); 969-76.
Karlson, B, Eek, F, Hansen ÅM, Garde AH, Ørbæk P. (2011) Cortisol variability and self-reports in the measurement of work-related stress. Stress and Health (E-pub-ahead-of-print).
Hahn, IH, Grynderup, MB, Dalsgaard, SB, Thomsen, JF, Hansen, ÅM, Kærgaard, A, Kærlev, L Mors, O, Ruguiles, R, Mikkelsen, S, Bonde, JP, Kolstad, HA. (2011) Does outdoor work during the winter season protect against depression and mood difficulties? SJWEH (E-pub-ahead-of-print).
Garde, AH, Albertsen, K, Persson, R, Hansen, ÅM, Rugulies, R. (2011) Bi-directional associations between psychological and physiological arousal and sleep quality. Beh Sleep Med (Accepted).
Persson, R, Hansen, ÅM, Garde, AH, Kristiansen, J, Nordander, C, Balogh, I, Ohlsson, K, Östergren, P-O, Ørbæk. (2011) Can the Job Content Questionnaire be used to assess structural and organisational properties of the work environment? IAOEH (E-pub-ahead-of-print).
Kærlev, L, Kolstad, HA, Hansen, ÅM, Thomsen, JF, Kærgaard, A, Ruguiles, R, Mikkelsen, S, Andersen, JH, Mors, O, Bonde, JP. (2011) Are risk estimates biased in follow-up studies of psychosocial factors with low base-line participation? BMC Public Health. (E-pub-ahead-of-print)
Hansen, ÅM, Garde, AH, Jensen, MA. (2011) Biological measures and the psychosocial working environment. Chapter 7 in ‘Biomarkers and human biomonitoring’ by the Royal Society of Chemistry in the Toxicology series. Edited by Professors Lisbeth Knudsen and Domenico Franco Merlo. 87-114.
Jensen, MA, Hansen, ÅM, Abrahamsson, P, Nørgaard, AW. (2011) Development and evaluation of a liquid chromatography tandem mass spectrometry method for simultaneous determination of salivary melatonin, cortisol and testosterone. J Chrom B. (E-pub-ahead-of-print)
Eek F, Karlson B, Garde AH, Hansen ÅM, Ørbæk P. (2011) Cortisol, sleep, and recovery - some gender differences but no straight associations. PNEC (Accepted).
Participation in research programs/projects
Selected research programs/projects during the past 5 years:
2011- Luxar – Health consequences of outdoor and night work with focus on light
2009- MODENA project – Negative behaviour at the workplace and mental health
2009- Cope-stress – an intervention project among employees with stress
2008- CAMB (Copenhagen Aging Midlife Biobank)
2008- An intervention study on time and length of working hours.
2008- Organizational changes, stress and health, An intervention project among civil servants
2008- Stress and Noise at the workplace
2008-2010 Nordic Network on bullying at the workplace
2006-2009 PRISME project: Occupational risk factor in development of depression, fatigue, and stress. Work place survey. In collaboration with Departments of Occupational Medicine at Hospitals in Herning, Århus, and Glostrup
2006-2009 A 3-year prospective study of bullying in Danish workplaces
Reviewer activity
1993- Analytica Chimica Acta, Analytical Chemistry, Archives of General Psychiatry, Basic & Clinical Pharmacololy & Toxicology, J Psychiatr Res, Biological Research for Nursing, European Journal of Applied Physiology, Eur J Epidemiol, International Archives of Occupational and Environmental Health, International Journal of Behavioral Medicine, International Sociaty of Exposure Analysis, Journal of Chromatography, Journal Of Exposure Science And Environmental Epidemiology, J Psychiatr Res, J Psychosom Res, Psychosom Med, Occup Environ Health, Psychoneuroendocrinology, Scand J Public Health, Scandinavian Journal of Work Environment and Health, Talanta, Stress, The Science of the Total Environment, Work and Stress.
Assessor activity
2010 Evaluating panel in the 7th European frame program
2007 Evaluation panel in the Economic Social Research Council (ESRC) UK’s leading research and training agency addressing economic and social concerns.
2006 Evaluation panel of the Italian Ministry for Education University and Research (MIUR)
2006 The Swedish Council for Working Life and Social Research
2003 Evaluation Panel Member of the 6th Panel of the Marie Curie Fellowships of the Human Potential Programme, European Commission
2001 Evaluation Panel Member of the 5th Panel of the Marie Curie Fellowships of the Human Potential Programme, European Commission
Supervisor activity
1995- Supervisor for more than 45 bachelor and graduate student from University of Copenhagen, The Danish Pharmaceutical University, The Danish Technical University, The Danish University of Education, Denmark and University of Padua, Italy.
1999-2003 Supervisor for Karin Sørig Hougaard (PhD) University of Copenhagen
1998-2001 Supervisor for Rikke Nikolajsen (PhD) The Royal Danish School of Pharmacy
1995-1998 Supervisor for Anne Helene Garde (PhD) University of Copenhagen
2008- Supervisor for Anette Werner (PhD) University of Århus
2008- Supervisor for Zara Stockholm (PhD) University of Århus
2009- Supervisor for Matias Grynderup (PhD) University of Århus
2009- Supervisor for Rikke Hinge (PhD) University of Copenhagen
2010- Supervisor for Marianne Vammen (PhD) University of Copenhagen
2010- Supervisor for Maria Gullander (PhD) University of Copenhagen
2011- Supervisor for Laura Francioli (PhD) University of Milan
External examiner of PhD
2011 Assessor in Occupational Medicine, Southern University of Denmark
2007 Mid-term assessment of a PhD, University of Lund, Sweden
Honorary offices
2001 Expert-Evaluator DG Research, Directorate L. Science, Research and Development, European Commission
1992 Award for Younger analytical scientists sponsored by Analytica Chimica Acta
Administrative experience
1998–2000
2001-2005 Deputy chairman in the joint council at The National Research Centre for the Working Environment
1995-2000 Substitute for the Manager of Research at the Reference laboratory at AMI
1997- Shop steward for ‘Agronomer, bromatologer, dyrlæger, og farmaceuter’ at AMI
1980-82 Member of the staff-student committee at the Royal Danish School of Pharmacy
1978-1980 Member of the council for the Institute of Physics at the Royal Danish School of Pharmacy
Other skills
Computer literacy (Various statistical softwares (SAS, SPSS, Minitab, database managements, word processing)
French (reading simple text)
German (reading simple text)
Fund-raising (only support to scientific work related to biomarkers are stated)
2011- Luxar – Health consequences of outdoor and night work with focus on light. AMFF/ DKK 5.0 mill of which 1.3 mill for NFA
2010- COPE-stress – Rehabilitation of individuals on sick-leave due to stress. TRYGFONDEN/ DKK 3.5 mill (0.3 for NFA)
2009- MODENA project – Negative behaviour at the workplace and mental health. AMFF/ DKK 5.6 mill (1.2 mill for NFA)
2009- Mental training and birth giving, NORDEA/ 1,5 mill Dkr (0.220 mill for NFA)
2009- Copenhagen aging midlife biobank (CAMB). VELUX/ DKK 19 mill, DKK approx. 4 mill to NFA
2008- Stress among parents to small children. FAS/ SEK 2.0 mill (0.260 mill for NFA)
2008- An intervention study on time and length of working hours. AMFF/ DKK 4.5 mill
2008- Nordic Network on bullying at the workplace. 150.000 DKK per year. Nordic Council of Ministers
2007- Network on cortisol as a measure of job stress. Vetenskabsråtet/ SEK 120.000
2006- Occupational risk factor in development of depression, fatigue, and stress. Work place survey. In collaboration with Departments of Occupational Medicine at Hospitals in Herning, Århus, and Glostrup. DKK 5 mill. Lundbeck supported the project with two PhD’s and genetic testing with DKK 4.8 mill. (Approx 1.6 mill for NFA)
2006-2009 A 3-year prospective study of bullying in Danish workplaces. AMFF/ DKK 8.9 mill
2006-2009 Intra- and inter-individual variations in key biomarkers within the general population. In collaboration with University of Copenhagen and a number of institutions in EU countries. EU 248.000 for NFA DKK. 150.000.
2003-2006 Night-time-work, melatonin and risk of breast cancer among registered nurses. DKK. 125.000
2002-2005 Interaction between physical and mental workload and incidence of musculoskeletal disease in women and men with equal repetitive work. DKK. 261.000
2002-2005 Stress reactivity in subjects with electromagnetic and chemical hypersensitivity. DKK. 400.000
2000-2004 Stress reduction. An intervention study. DKK 300.000
2000-2002 Influence of production systems on psychological and physical job strain – A Quasi-experimental field study. DKK 200.000.
2001-2006 A model for co-ordination of data from measurements of physiological effects of occupational stressors. Nordic Council of Ministers. DKK. 540.200.
1999-2000 A Nordic strategy for measurement of physiological indicators as measure of effect from occupational stressors. Nordic Council of Ministers. DKK. 382.000
1995-1996 Biological and seasonal variation of biomarkers of stress in healthy female. The Health Insurance Fund. DKK. 120.000.