Arbejdsopgaver
Chef for en række forskningsgrupper, som beskæftiger sig med arbejdsmiljømæssige aspekter af toksikologi, høreskader, hud- og luftvejsallergi, molekylærbiologi og kræftforskning, mikrobiologiske problemstillinger, indeklimakemi, luftvejsirritation og sundhedsmæssige aspekter af fine og ultrafine partikler.
Aktuel forskning
Den del af min tid jeg bruger på selv af være aktiv forsker går primært til mikrobiel genetik. Specielt problemstillingen omkring mikrobiologiske bekæmpelsesmidler og arbejdsmiljø.
Udvalgte publikationer
Jensen G.B., N. Fisker, T. Sparsø, L. Andrup. 2005. Discrimination within the Bacillus cereus group using gyrB sequencing and PCR-RFLP. International Journal of Food Microbiology 104(1):113-20.
Wilcks A, Smidt L, Bahl MI, Hansen BM, Andrup L, Hendriksen NB, Licht TR. 2008. Germination and conjugation of Bacillus thuringiensis subsp. israelensis in the intestine of gnotobiotic rats. J Appl Microbiol. 104(5):1252-9.
Andrup L, Barfod KK, Jensen GB and Smidt L. 2008. Detection of large plasmids from the Bacillus cereus group. Plasmid 59(2):139-43.
Apetroaie-Constantin C, Shaheen R, Andrup L, Smidt L, Rita H, Salkinoja-Salonen M. 2008. Environment driven cereulide production by emetic strains of Bacillus cereus. Int J Food Microbiol. 127(1-2):60-7.
Andrup, L., B. H. Nielsen, and S. Kølvraa. 1990. Biosafety considerations in industries using recombinant-DNA based production methods. Scand.J.Work.Environ.Health 16:85-95.
Andrup, L., J. Damgaard, and K. Wassermann. 1993. Mobilization of small plasmids in Bacillus thuringiensis subsp. israelensis is accompanied by specific aggregation. J.Bacteriol. 175(20):6530-6536.
Jensen, G. B., A. Wilcks, S. S. Petersen, J. Damgaard, J. A. Baum and L. Andrup. 1995. The genetic basis of the aggregation system in Bacillus thuringiensis subsp. israelensis is located on the large conjugative plasmid pXO16. J.Bacteriol.177:2914-2917.
Andrup, L., G.B. Jensen, A. Wilcks, and L. Smidt. 1996. Mobilization of "non-mobilizable" plasmids by the aggregation-mediated aggregation system of Bacillus thuringiensis. Plasmid36:75-85.
Jensen, G. B., L. Andrup., A. Wilcks, L. Smidt., and O. M. Poulsen. 1996. The aggregation-mediated conjugation system of Bacillus thuringiensis subsp. israelensis: host range and kinetics of transfer. Curr. Microbiol.33:228-236.
Andrup, L., L. Smidt, K. Andersen, and L. Boe. 1998. Kinetics of conjugative transfer: a study of the plasmid pXO16 from Bacillus thuringiensis subsp. israelensis. Plasmid40:30-43.
Andrup L. 1998. Conjugation in Gram-positive bacteria and kinetics of plasmid transfer. APMIS 84:47-55.
Wilcks, A., L. Smidt, O. A. Økstad, A-.B. Kolstø, J. Mahillon and L. Andrup. 1999. Replication mechanism and sequence analysis of the replicon of pAW63, a conjugative plasmid from Bacillusthuringiensis. J. Bacteriol.181: 3193-3200.
Andrup, L and K. Andersen. 1999. A comparison of the kinetics of plasmid transfer in the conjugation systems encoded by the F plasmid from Escherichia coli and plasmid pCF10 from Enterococcus faecalis. Microbiology145: 2001-2009.
Zhiming, Y., J. Eilenberg, L. Andrup, and B. M. Hansen. 2002. Detection of enterotoxin genes in mosquito-larvicidal Bacillus species. Curr. Microbiol.45:221-5.
Jensen, G. B., P. Larsen, B. L. Jacobsen, B. Madsen, L. Smidt, and L. Andrup. 2002. Bacillus thuringiensis in fecal samples from greenhouse workers after exposure to B. thuringiensis-based pesticides. Appl. Environ. Microbiol. 68:4900-4905.
Andrup L, G.B. Jensen, A. Wilcks, L. Smidt, L. Hoflack, J. Mahillon. 2003. The patchwork nature of rolling-circle plasmids: comparison of six plasmids from two distinct Bacillus thuringiensis serotypes. Plasmid 49(3):205-32.
Van der Auwera GA, Andrup L, Mahillon J. Conjugative plasmid pAW63 brings new insights into the genesis of the Bacillus anthracis virulence plasmid pXO2 and of the Bacillus thuringiensis plasmid pBT9727. BMC Genomics. 2005 Jul 26;6:103
Hoton FM, Andrup L, Swiecicka I, Mahillon J. The cereulide genetic determinants of emetic Bacillus cereus are plasmid-borne. Microbiology. 2005 Jul;151(Pt 7):2121-4.
Medlemskab og netværk
Dansk Mikrobiologisk Selskab
Kemiingeniørgruppen, Levnedsmiddelselskabet
Selskab for Arbejdsmiljø
American Society for Microbiology
De Danske Ølentusiaster
Dansk Fødevareforsknings Ekspertgruppe for Fugleinfluenza
Ansættelser
| 2004 |
Projektkoordinationschef (AMI) |
| 1999 |
Forskningschef (Afdeling for Kemisk Arbejdsmiljø, AMI) |
| 1997 |
Foskningsleder (Afdeling for Mikrobiologi, Irritation og Allergi, AMI) |
| 1994 |
Seniorforsker i molekylærbiologi (AMI) |
| 1990 |
Ph.D.-studerende (AMI) |
| 1988 |
Toksikologisk-biologisk Afdeling (AMI) |
| 1987 |
Produktregistret (AMI), |
| 1986 |
Forsknings- og undervisningsvikar (Laboratoriet for Mikrobiologi, DTU) |
