CV

Nicklas Raun Jacobsen

nrj@arbejdsmiljoforskning.dk
+45 3916 5279

Fødselsdato

13. november 1975

Uddannelse 

2008   Ph.D. i sundhedsvidenskab

2002   Cand. Scient. i biologi, Københavns Universitet

Erhvervserfaring

2008-

Post. Doc. Det Nationale Forskningscenter for Arbejdsmiljø

2004-2008

Ph.D., Det Nationale Forskningscenter for Arbejdsmiljø, 2004

2004

Forskningsassistent, Arbejdsmiljøinstituttet

2003-2004

Forskningsassistent, Fødevareinstituttet

2002-2003

Forskningsassistent, Arbejdsmiljøinstituttet

2001-2002 

Speciale, Arbejdsmiljøinstituttet


Publikationer i internationale tidskrifter (18)

24. Danielsen PH, Loft S, Jacobsen NR, Jensen KA, Autrup H, Ravanat JL, Wallin H & Møller P. Oxidative stress, inflammation and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter. Accepted for publication in Toxicological Sciences. Epub.
23. Jacobsen NR, White P, Gingerich J, Møller P, Saber AT, Douglas G, Vogel U & Wallin H. Mutation spectrum in FE1-Muta™Mouse lung epithelial cells exposed to nanoparticulate carbon black. Accepted for publication in Environmental and Molecular Mutagenenesis. Epub.
22. Vesterdal LK, Folkmann JK, Jacobsen NR, Sheykhzade M, Wallin H, Loft S & Møller P. Pulmonary exposure to carbon black nanoparticles and vascular effects. Particle and Fibre Toxicology 2010;7:33.
21. Sharma AK, Schmidt B, Frandsen H, Jacobsen NR, Larsen EH & Binderup ML. Genotoxicity of unmodified and organo-modified montmorillonite. Mutation Research – Genetic Toxicology and Environmental Mutagenesis. 2010;700(1-2):18-25.
20. Møller P, Jacobsen NR, Folkmann JK, Danielsen PH, Mikkelsen L, Hemmingsen JG, Vesterdal LK, Forchhammer L, Wallin H & Loft S. Role of oxidative damage in toxicity of particulates. Free Radical Research. 2010;44(1):1-46.
19. Sadauskas E, Jacobsen NR, Dansher G, Stoltenberg M, Vogel U, Larsen A, Kreyling W & Wallin H. Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation. Chemistry Central Journal. 2009;3:16.
18. Vesterdal LK, Folkmann JK, Jacobsen NR, Sheykhzade M, Wallin H, Loft S & Møller P. Modest vasomotor dysfunction induced by low doses of C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis. Particle and Fibre Toxicology 2009;6:5.
17. Jacobsen NR, Møller P, Jensen KA, Vogel U, Ladefoged O, Loft S & Wallin H. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice. Particle and Fibre Toxicology 2009;6:2.
16. Folkmann JK, Risom L, Jacobsen NR, Wallin H, Loft S & Møller P. Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-walled Carbon Nanotubes. Environmental Health Perspectives 2009;117(5):703-708.
15.

Jacobsen NR, Pojana G, White P, Møller P, Cohn CA, Korsholm KS, Vogel U, Marcomini A, Loft S & Wallin H. Genotoxicity, Cytotoxicity and Reactive Oxygen Species Induced by Single-Walled Carbon Nanotubes and C60 Fullerenes in the FE1-Muta™Mouse Lung Epithelial Cells. Environ Mol Mutagen 2008;49(6):476-487.

14. Jacobsen NR, Møller P, Cohn CA, Loft S, Vogel U & Wallin H. Diesel exhaust particles are mutagenic in FE1-Muta™Mouse lung epithelial cells. Mutat Res. 2008;641(1-2):54-7.
13. Sharma AK, Jensen KA, Rank J, White PA, Lundstedt S, Gagne R, Jacobsen NR, Kristiansen J, Vogel U & Wallin H. Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air. Mutat Res. 2007;633(2):95-111.
12. Jacobsen NR, Saber AT, White P, Møller P, Pojana G, Vogel U, Loft S, Gingerich J, Soper L, Douglas GR & Wallin H. Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells. Environ Mol Mutagen. 2007;48(6):451-61.
11. Krause M, Josefsen MH, Lund M, Jacobsen NR, Brorsen L, Moos M, Stockmarr A & Hoorfar J. Comparative, collaborative, and on-site validation of a TaqMan PCR method as a tool for certified production of fresh, campylobacter-free chickens. Appl Environ Microbiol. 2006;72(8):5463-8.
10.

Saber AT, Jacobsen NR, Bornholdt J, Kjaer SL, Dybdahl M, Risom L, Loft S, Vogel U & Wallin H. Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor. Part Fiber Toxicol. 2006&20;3:4.

9. Jacobsen NR, Bogdanovich T, Skurnik M, Lübeck PS, Ahrens P & Hoorfar J. A real-time PCR assay for the specific identification of serotype O:9 of Yersinia enterocolitica. J Microbiol Methods. 2005;63(2):151-6.
8. Jacobsen NR, Raaschou-Nielsen O, Nexø B, Wallin H, Overvad K, Tjønneland A & Vogel U. XRCC3 polymorphisms and risk of lung cancer. Cancer Lett. 2004 Sep 15;213(1):67-72.
7. Josefsen MH, Jacobsen NR & Hoorfar J. Enrichment followed by real-time PCR for rapid detection and as a tool for quantitative risk assessment of foodborne thermotolerant campylobacters. Appl Environ Microbiol. 2004;70(6):3588-92.
6. Vogel U, Laros I, Jacobsen NR, Thomsen BL, Bak H, Olsen A, Wallin H, Overvad K, Tjønneland A, Nexø BA & Raaschou-Nielsen O. Two regions in chromosome 19 q13.2-3 are associated to risk of lung cancer. Mutat. Res. 2004;546:65-74.
5. Jacobsen NR, Nexø BA, Olsen A, Overvad K, Wallin H, Tjønneland A & Vogel U. No association between the DNA repair gene XRCC3 Thr241Met polymorphism and breast or skin cancer risk. Cancer Epidemiology Biomarkers and Prevention 2003;12:584-585.
4. Vogel U, Nexø BA, Olsen A, Thomsen B, Jacobsen NR, Wallin H, Overvad K & Tjønneland A. No association between OGG1 Ser326Cys polymorphism and breast cancer risk. Cancer Epidemiology Biomarkers and Prev. 2003;2:170-1.
3. Yin J, Rockenbaur E, Hedayati M, Jacobsen NR, Vogel U, Grossman L, Bolund L & Nexø BA. Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of basal cell carcinoma. Cancer Epidemiology Biomarkers and Prev. 2002;11:1449-1453.
2.

Rockenbaur E, Bendixen MH, Bukowy Z, Yin J, Jacobsen NR, Hedayati M, Vogel U, Grossman L, Bolund L & Nexø A. Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts. Carcinogenesis 2002;7:1149-1153.

1. Jürgensen CW, Jacobsen NR, Emri T, Eriksen SH & Pocsi I. Glutathione metabolism and dimorphism in Aureobasidium pullulans. J of Basic Microbiology 2001;41:131-137. CWJ and NRJ shared first author. 

 18.05.2009
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