Peder Wolkoff

Peder Wolkoff

Arbejdsopgaver

Adjungeret professor ved Kemisk Institut, Københavns Universitet.

Underviser ved ELITE uddannelsen "Environmental Chemistry and Health" ved Københavns Universitet

Aktuel forskning

  • CISBO (Center for Indeklima og Sundhed i Boliger) - 2009-2014 -- RealDania
  • Luftvejseffekter af spraymidler til imprægnering – vurdering ud fra kombineret biologisk og fysisk/kemisk karakterisering - 2009-2012 - Arbejdsmiljøforskningsfonden
  • EPHECT (Emissions, Exposure Patterns and Health Effects of Consumer Products in the EU) - 2010-2013 - EU Health Programme 
  • OFFICAIR (Indoor Air Pollution and Health Risks of Modern Office Buildings)  -  2011-2014  - 7th Framework Programme

Forskningsinteresser

Indeklimakemi og sundhedseffekter:

  • Hvordan kan indeklimasymptomer forklares ud fra kemiske påvirkninger i samspil med andre indeklima-risikofaktorer?
  • Jeg fokuserer på slimhindeirritation i luftvejene, og samspillet mellem lugt og irritation.
  • Jeg fokuserer særligt på årsager til øjenirritation og luftvejseffekter i kontormiljøet.
  • Måling af byggematerialers emission, sundhedsmæssige betydning og indeklimamærkning.
  • Hvilken betydning har nano-partikler i indeklimaet.

Publikationer

 

2011
Nørgaard, A.W., Janfelt, C., Benassi, M., Wolkoff, P., Lauritsen, F.R.
Electrospray and desorption ionization analysis of reactive organo-
functionalized silanes in nano film products, J Mass Spectrometry, 46 (2011) 402-410.

 

2010-2009 

Wolkoff, P. Ocular discomfort by environmental and personal risk factors altering the precorneal tear film. Toxicology Letters, 199 (2010) 203-212. 
Nørgaard, A.W., Wolkoff, P., Lauritsen, F.R. Characterization of nano film spray products, Chemosphere, 80 (2010) 1377-1386. 
Wolkoff, P., Nielsen, G.D. Non-cancer effects of formaldehyde and relevance for setting an indoor air guideline. Environment International, 36 (2010) 788-799. 
Nielsen, G.D., Wolkoff, P. Cancer effects of formaldehyde: A proposal for an indoor air guideline value. Archives of Toxicology, 84 (2010) 423-446. 
Nørgaard, A.W., Larsen, S.T., Hammer, M., Poulsen, S.S., Jensen, K.A., Nielsen, G.D., Wolkoff, P. Lung damage in mice after inhalation of nanofilm spray products: The role of perfluorinatiion and free OH groups, Toxicological  Sciences, 116 (2010) 216-224. 
Nørgaard, A.W., Jensen, K.A., Janfelt, C., Lauritsen, F.R., Clausen, P.A., Wolkoff, P. Release of VOCs and particles during use of nano film spray products, Environmental Science & Technology., 43 (2009) 7824-7830.
Vibenholt, A., Nørgaard, A.W., Clausen, P.A., Wolkoff, P. Formation and stability of secondary ozonides from monoterpenes studied by mass spectrometry, Chemosphere, 76 (2009) 572-577.
Carslaw, N., Langer, S., Wolkoff, P. Where is the link between reactive indoor air chemistry and health effects? Atmospheric Environment, 43 (2009) 3808-3809.

 

2008-2007

Clausen, P.A. Knudsen, H.N., Larsen, K., Wolkoff, P., Wilkins, C.K. Use of thermal desorption gas chromatography olfactometry/mass spectrometry (TD-GC-O/MS) for comparison of identified and unidentified odor active compounds emitted from building products containing linseed oil", J. Chromatography A, 1210 (2008) 203-210.
Wolkoff, P., Clausen, P.A., Larsen, K., Hammer, M. and Nielsen, G.D. Acute airway effects of ozone-initiated d-limonene chemistry: Importance of gaseous products. Toxicology Letters, 181 (2008) 171-176.
Wolkoff, P. "Healthy" eye in office-like environments. Environment International, 34 (2008) 1204-1214.
Nielsen, P.K., Søgaard, K., Skotte, J., Wolkoff, P. Ocular surface area and human eye blink frequency during VDU work - the effect of monitor position. European J. Physiology, 103 (2008) 1-7.
Nørgaard, A.W., Nøjgaard, J.K., Clausen, P.A., Wolkoff, P. "Secondary ozonides of substituted cyclohexenes: A new class of pollutants characterized by collision-induced dissociation mass spectrometry using negative chemical ionization", Chemosphere, 70 (2008) 2032-2038.
Nøjgaard, J.K., Nørgaard, A.W. and Wolkoff, P. On-line analysis of secondary ozonides from cyclohexene and d-limonene ozonolysis using atmospheric sampling Townsend discharge ionization mass spectrometry, Atmospheric Environment 41 (2007) 8345-8354.
Wolkoff, P., Kjærgaard, S.K. The dichotomy of relative humidity on indoor air quality. Environmrnt International, 33 (2007) 850-857.
Cain, W.S., Schmidt, R. and Wolkoff, P. Olfactory detection of ozone and d-limonene: Reactants in indoor spaces, Indoor Air, 17 (2007) i337-347.
Nielsen, G.D., Wolkoff, P., Alarie Y. Sensory irritation: Risk assessment approaches. Regulatory Toxicology and Pharmacology, 48 (2007) 6-18.
Nielsen, G.D., Larsen, S.T., Olesen, O., Løvik, M., Poulsen, L.K., Glue, C., Wolkoff, P. IgE-mediated sensitization and airway diseases. Are indoor chemicals adjuvants? Indoor Air, 17 (2007) 226-235.
Wilkins, C.K., Wolkoff, P., Knudsen, H.K., Clausen, P.A., "The importance of information for perceived air quality - organic vs synthetic building materials", Indoor Air, 17 (2007) 130-134.
Nøjgaard, J.K., Nørgaard, A.W. and Wolkoff, P. Atmospheric sampling of some endocyclic alkene secondary ozonides using Townsend discharge ionization mass spectrometry, Int. J. Mass Spectrometry, 263 (2007) 88-93.
Nøjgaard, J.K., Larsen, K. and Wolkoff, P. Atmospheric sampling Townsend discharge ionisation mass spectrometry for analysis of gas-phase mixtures. International Journal of Mass Spectrometry, 260 (2007) 49-56.
Clausen, P.A., Xu, Y., Kofoed-Sørensen, V., Little, J.C., Wolkoff, P. The influence of humidity on the emission of di-(2-ethylhexyl) phthalate (DEHP) from vinyl flooring in the emission cell "FLEC", Atmospheric Environment, 41 (2007) 3117-3124.
Knudsen, H.N., Clausen, P.A., Wilkins, C.K. and Wolkoff, P. Sensory and chemical evaluation of odorous emissions from building products with and without linseed oil. Building and Environment, 42 (2007) 4059-4067.

 

2006-2005

Wolkoff, P., Nøjgaard, J.K., Franck, C., Skov, P. Udtørrer det moderne kontormiljø øjnene? Ugeskrift for læger, (2006), 3893-3896.
Nørgaard, A.W., Nøjgaard, J.K., Larsen, K., Sporring, S. Wilkins, C.K., Clausen, P.A., Wolkoff, P. Secondary limonene endo-ozonide: A major product from gas-phase ozonolysis of R-(+)-limonene at ambient temperature. Atmospheric Environment, 40 (2006) 3460.3466
Wolkoff, P., Nøjgaard, J.K., Franck, C. Skov, P. The modern office environment desiccates the eyes? Indoor Air, 16 (2006) 258-265.
Nøjgaard, J.K., Stenby, C., Bilde, M., Nielsen, O.J., Wolkoff, P. The Effect of NOx on Particle Formation during ozonolysis of two abundant monoterpenes indoors",Atmos. Environ.,40 (2006) 1030-1042.
Wolkoff, P., Wilkins, C.K., Clausen, P.A., Nielsen, G.D. "Organic compounds in office environments - Sensory irritation, odor, measurements, and the role of reactive chemistry", Indoor Air, 16 (2006) 7-19.
Nielsen, G.D., Larsen, S.T., Hougaard, K.S., Hammer, M., Wolkoff, P., Clausen, P.A., Wilkins, C.K., Alarie, Y. "Mechanism of acute inhalation effects of (+) and (-)-a-pinene in BALB/c mice", Pharmacology & Toxicology, 96 (2005) 420-428.
Nøjgaard, J.K., Christensen, K.B., Wolkoff, P. "The effect on human eye blink frequency of exposure to limonene oxidation products and methacrolein", Toxicology Letters, 156 (2005) 241-251.
Wolkoff, P., Salthammer, T., Woolfenden, E.A. "Emission Cells and Comparison to Small Chambers for Materials Emissions Testing", Gefahrstoffe - Reinhaltung der Luft 65 (2005) 93-98.
Wolkoff, P., Nøjgaard, J.K., Troiano, P. and Piccoli, B. "Eye complaints in the office environment: Precorneal tear film integrity influenced by eye blinking efficiency", Occupational Environmental Medicine, 62 (2005) 4-12.

 

2004-2003

Klenø, J. and Wolkoff, P. "Changes in Eye Blink Frequency as a Measure of Trigeminal Stimulation by Exposure to Limonene Oxidation Products, Isoprene Oxidation Products and Nitrate Radicals", Int. Arch. Occup. Environ. Health, 77 (2004) 235-243.
Clausen, P.A., Hansen, V., Gunnarsen, L., Afshari, A., Wolkoff, P. "Emission and sorption of di(2-ethylhexyl)phthalate from PVC flooring into air and dust in FLEC and CLIMPAQ. Environmental Science & Technology 39 (2004) 2531-2537.
Wolkoff, P., Skov, P., Franck, C., Petersen, L.P "Eye irritation and environmental factors in the office environment. Hypotheses, causes, and a physiological model", Scan J Work, Environment & Health, 29 (2003) 411-430.
Wilkins, C.K., Wolkoff, P., Clausen, P.A., Hammer, M. and Nielsen, G.D. "Upper airway irritation of terpene/ozone oxidation products (TOPs). Dependence on reaction time, relative humidity, and initial ozone concentration, Toxicology Letters, 143 (2003) 109-114.
Knudsen, H.N., Nielsen, P.A., Clausen, P.A., Wilkins, C.K. and Wolkoff, P. "Sensory evaluation of emissions from selected building products exposed to ozone", Indoor Air, 13 (2003) 223-231.
Wolkoff, P. "Trends in Europe to Reduce the Indoor Air Pollution of VOCs", Indoor Air, 13 (Suppl. 6) (2003) 5-11.

 

2002-2000

Vejrup, K.V. and Wolkoff, P. "Linear alkylbenzene sulphonates in indoor floor dust". The Science and the Total Environment, 300 (2002) 51-58.
Klenø, J.G., Wolkoff, P., Clausen, P.A., Wilkins, C.K. and Pedersen, T. "Degradation of the adsorbent Tenax TA by nitrogen oxides, ozone, hydrogen peroxide, OH radical, and limonene oxidation products", Environmental Science & Technology, 37 (2002) 4121-4126.
Rohr, A., Wilkins, C.K., Clausen, P.A., Hammer, M., Nielsen, G.C., Wolkoff, P. and Spengler, J.D. "Upper airway and pulmonary effects of oxidation products of (+)-a-Pinene, d-limonene and isoprene in BALB/c mice", Inhalation Toxicology, 14 (2002) 663-684.
Wolkoff, P. and Nielsen, G.D. "Organic compounds in indoor air - Their relevance for perceived indoor air quality", Atmospheric Environment, 35 (2001) 4407-4417.
Klenø, J.G., Clausen, P.A., Weschler, C., Wolkoff, P. "Determination of ozone removal rates by selected building products using the FLEC emission cell", Environmental Science & Technology, 35 (2001) 2548-2553.
Wilkins, C.K., Clausen, P.A., Wolkoff, P., Larsen, S.T., Hammer, M., Larsen, K., Hansen, V., Nielsen, G.D. "Formation of strong airway irritants in a model mixture of isoprene/ozone", Environmental Health Perspectives, 109 (2001) 937-941.
Clausen, P.A., Wilkins, C.K., Wolkoff, P. and Nielsen, G.D. "Chemical and biological evaluation of a reaction mixture of R-(+)-limonene/ozone: Formation of strong airway irritants", Environmental International, 26 (2001) 511-522.
Larsen, S.T., Hougaard, K.S., Hammer, M., Alarie, Y., Wolkoff, P., Clausen, P.A., Wilkins, C.K. and Nielsen, G.D. "Effects of R-(+)- and R-(-)-limonene on the respiratory tract in mice", Human and Experimental Toxicology, 19 (2000) 457-466.
Peitersen, J., Brohus, H., Hyldgaard, C.E., Nielsen, J.B., Valbjørn, O., Hauschildt, P., Kjærgaard, S.K., Wolkoff, P. "The effect of renovating an office building on occupants' comfort and health", Indoor Air, 11 (2001) 10-25.
Wolkoff, P., Clausen, P.A., Wilkins, C.K., and Nielsen, G.D. "Strong airway irritants formed in terpene/ozone mixtures", Indoor Air, 10 (2000) 82-91.

 

1999-1972

76 peer-reviewed publications - see extended CV

Tillidshverv

  • Editorial board member: Indoor Air
  • Elected fellow of the Academy of ISIAQ (International Society of Indoor Air Quality and Climate)
  • Temporary Advisor for WHO  

Æresbevisninger og priser

2000   Best poster Award at Healthy Buildings ´00 (IAIAS)
1999 Best Paper Award in Indoor Air Journal (1996-1998) (IAIAS)
1998 Scandinavian Indoor Climate Award (ISS Danmark)
1997 Elected member (The International Academy of Indoor Air Sciences)

Uddannelse

1996 Dr.med. (indeklima) (Københavns Universitet)
1976-78   Post doctoral fellow (Ottawa Universitet)
1976 NATO Science Fellow (Amsterdams Univetsitet )
1976 Lic.scient. (Ph.D.) (org. kemi) (Københavns Universitet)
1972 Cand.scient. (org. kemi) (Københavns Universitet)
 29.03.2011
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