Arbejdsopgaver
Mine primære forskningsinteresser er luftvejsallergi og luftvejsirritation.
Aktuel forskning
Luftvejsallergigruppen har i øjeblikket fokus på at undersøge visse kemikalier for adjuvanseffekt, d.v.s. vi undersøger om stofferne har evnen til at forstærke den allergifremkaldende effekt af allergener som fx. pollen og husstøvmideallergener.
Udvalgte publikationer
- C.K Wilkins, S.T. Larsen, M. Hammer, O.M. Poulsen, P. Wolkoff and G. D. Nielsen. Respiratory effects in mice exposed to airborne emissions from Stachybotrys chartarum and implications for risk assessment. Pharmacol. Toxicol., 1998, 83, 112-119.
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S.T. Larsen, K.S. Hougaard, M. Hammer, Y. Alarie, P. Wolkoff, P.A. Clausen, C.K. Wilkins and G.D. Nielsen. Effects of R(+) and S(-)-limonene on the respiratory tract in mice. Human Exp. Toxicol., 2000, 19, 400-409.
- C.K Wilkins, P.A. Clausen, P. Wolkoff, S.T. Larsen and G.D. Nielsen. Formation of strong airway irritants in a model mixture of isoprene/ozone/nitrogen dioxide. Environ. Health Perspect., 2001, 109, 937-941
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S.T. Larsen, R.M. Lund, G.D. Nielsen, P. Thygesen and O.M. Poulsen. Di-(2-ethylhexyl) phthalate possesses an adjuvant effect in a subcutaneous injection model with BALB/c mice. Toxicol. Letters, 2001, 125, 11-18.
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S.T. Larsen, J.S. Hansen, P. Thygesen, M. Begtrup, O.M. Poulsen and G.D. Nielsen. Adjuvant and immuno-suppressive effect of six monophthalates in a subcutaneous injection model with BALB/c mice. Toxicology 2001, 169, 37-51.
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S.T. Larsen, R.M. Lund, G.D. Nielsen, P. Thygesen and O.M. Poulsen. Adjuvant effect of di-n-butyl-, di-n-octyl-, di-iso-nonyl- and di-iso-decyl phthalate in a subcutaneous injection model using BALB/c mice. Pharmacol. Toxicol., 2002, 91, 264-272.
- G.D. Nielsen, J.S. Hansen, R.M. Lund, M. Bergqvist, S.T. Larsen, S.K. Clausen, P. Thygesen and O.M. Poulsen. IgE-mediated asthma and rhinitis. A role of allergen exposure. Pharmacol. Toxicol., 2002, 90, 231-242.
- K.F. Jepsen, A. Abildtrup and S.T. Larsen. Monophthalates promote IL-6 and IL-8 production in the human epithelial cell line A-549. Toxicol. in Vitro, 2004, 265-269.
Ansættelser
2002: Forsker ved luftvejsallergigruppen, Arbejdsmiljøinstituttet
1999: Ph.D.-studerende, Institut for Farmakologi, Danmarks Farmaceutiske Universitet
Uddannelse
2002: Ph.D.
1998: Farmaceut (Cand. pharm.)
