FreeTextSearch
 
search View English language version of this page
 
 
 

Occupational exposures and 20-year incidence of COPD: The European Community Respiratory Health Survey [Epub ahead of print]

Reference Lytras T, Kogevinas M, Kromhout H, et al. Occupational exposures and 20-year incidence of COPD: The European Community Respiratory Health Survey [Epub ahead of print]. Thorax 2018;
Udgivet: 2018
[Type] Videnskabelig artikel
[Resumé] BACKGROUND: Occupational exposures have been associated with an increased risk of COPD. However, few studies have related objectively assessed occupational exposures to prospectively assessed incidence of COPD, using postbronchodilator lung function tests. Our objective was to examine the effect of occupational exposures on COPD incidence in the European Community Respiratory Health Survey. METHODS: General population samples aged 20-44 were randomly selected in 1991-1993 and followed up 20 years later (2010-2012). Spirometry was performed at baseline and at follow-up, with incident COPD defined using a lower limit of normal criterion for postbronchodilator FEV1/FVC. Only participants without COPD and without current asthma at baseline were included. Coded job histories during follow-up were linked to a Job-Exposure Matrix, generating occupational exposure estimates to 12 categories of agents. Their association with COPD incidence was examined in log-binomial models fitted in a Bayesian framework. FINDINGS: 3343 participants fulfilled the inclusion criteria; 89 of them had COPD at follow-up (1.4 cases/1000 person-years). Participants exposed to biological dust had a higher incidence of COPD compared with those unexposed (relative risk (RR) 1.6, 95% CI 1.1 to 2.3), as did those exposed to gases and fumes (RR 1.5, 95% CI 1.0 to 2.2) and pesticides (RR 2.2, 95% CI 1.1 to 3.8). The combined population attributable fraction for these exposures was 21.0%. INTERPRETATION: These results substantially strengthen the evidence base for occupational exposures as an important risk factor for COPD
Link: http://dx.doi.org/10.1136/thoraxjnl-2017-211158
Bestilling: Denne udgivelse kan ikke bestilles fra NFA's Forlag
[Oprettet] 09.04.2018
 
Opdateret  09.04.2018
Kontakt: NFA's webredaktion
 
Sociale medieomtaler af denne artikel

Klik på cirklen for mere information om omtaler og deling af denne artikel.

Altmetric er en tjeneste, der registrerer sociale medieomtaler og delinger af referencer forskningsartikler, hvis læsere har linket unikt til artiklen (tidskriftets abstractside, DOI-link etc.). Tjenesten overvåger p.t. omtaler på udvalgte sociale medieplatforme.

Hvis cirklen viser "?", er der endnu ikke registreret omtaler på de overvågede medier.

Om betalingstidsskrifter
Mange videnskabelige tidsskrifter tager betaling for adgang til hele artiklen. Hvis du ikke har adgang til et bestemt tidsskrift, kan du benytte Bibliotek.dk. Her kan du søge efter artikler, bogtitler og tidsskrifter på tværs af de danske bibliotekssystemer.

Det letteste er at gå ind under "Flere søgemuligheder" på siden og så indtaste tidsskriftets navn i Feltet "Titel". Derved får du en oversigt over folke- eller forskningsbiblioteker, som abonnerer på det pågældende tidsskrift.

 
 
 

Det Nationale Forskningscenter for Arbejdsmiljø | Lersø Parkallé 105 | DK-2100 København Ø |

Tlf 39 16 52 00 | fax 39 16 52 01 | e-mail: nfa@arbejdsmiljoforskning.dk | CVR: 15413700 | EAN: 5798000399518

Vis desktop version
|WEBSITET ANVENDER COOKIES TIL AT HUSKE DIG OG DINE INDSTILLINGER.| Læs mere her